Displaying 11 - 20 of 24
E.g., 30 Mar 2020
E.g., 30 Mar 2020
11 Dec 2014


Electronic health records (EHR)support clinical management, administration, quality assurance, research, and service planning. The aim of this study was to evaluate a clinical data management programme to improve consistency, completeness and accuracy of EHR information in a large primary care centre with 10 General Practitioners (GPs). A Clinical Data Manager was appointed to implement a Data Management Strategy which involved coding consultations using ICPC-2 coding, tailore...

11 Nov 2014


Participants with the metabolic syndrome are at risk of developing type 2 diabetes and coronary heart disease. The aim of this study was to determine the role of lifestyle risk factors in the development of the metabolic syndrome with particular reference to physical activity, smoking and alcohol consumption. We performed a cross sectional study of the prevalence of CVD risk factors and glucose intolerance, including type 2 diabetes involving a group of 1473 men and women wer...

14 May 2014

The effect of work on blood pressure (BP) in a general population with appropriate adjustment for confounders is not well defined. High job control has been found to be associated with lower BP and with nocturnal BP dipping. However, with older workers this may be compromised and has not been studied extensively.


A cross-sectional study was carried out on a primary care-based sample (N=2047) aged 50-69 years. Data were collected on sociodemographic factors...

13 Nov 2013


To compare diabetes risk assessment tools in estimating risk of developing type 2 diabetes (T2DM) and to evaluate cardiometabolic risk profiles in a middle-aged Irish population.


Future risk of developing T2DM was estimated using 7 risk scores, including clinical measures with or without anthropometric, biological and lifestyle data, in the cross-sectional Mitchelstown cohort of 2,047 middle-aged men and women. Cardiometabolic phenotypes including marke...

6 Aug 2013

BACKGROUND The Dietary Approaches to Stop Hypertension (DASH) Trial provides critical data on the impact of a specific diet pattern (low in salt, fat, and processed foods and high in fruit and vegetables) on blood pressure (BP). The effect of compliance with a DASH-type diet on BP in a general population sample is less well defined. We studied associations between a DASH style diet and BP.

METHODS We used cross-sectional data from a study of men and women aged 47–73 years (n = 2,047)....

11 Jul 2012
Why was the cohort set up?

Cardiovascular disease (CVD) including ischaemic heart disease and cerebrovascular disease is among the leading causes of mortality worldwide,1 and in Ireland, coronary heart disease death rates are among the highest in Europe.2 Although it has previously been reported that only 50% of CVD can be attributed to traditional risk factors,3,4 it is now recognized that these factors occur much more frequently in people with CVD,5,6 with most of the population attributabl...

24 Apr 2012



There is a heightened need for the practitioner to be alert to the determinants of functional limitations and disabilities owing to the ageing workforce.


This study investigated the association between work type and disability in older age in both the paid and the previously unexplored, unpaid worker (household labour).


Data on demographic factors, physical measurements, work history and functional status were collec...

13 Jun 2008



Most cardiovascular disease (CVD) occurs in the presence of traditional risk factors, including hypertension and dyslipidemia, and these in turn are influenced by behavioural factors such as diet and lifestyle. Previous research has identified a group at low risk of CVD based on a cluster of inter-related factors: body mass index (BMI) < 25 Kg/m2, moderate exercise, alcohol intake, non-smoking and a favourable dietary pattern. The objective of this study w...

22 Sep 2005



A cluster of interrelated factors: a body mass index (BMI) < 25 kg/m(2), moderate exercise and alcohol intake, non-smoking and a favourable dietary pattern has been linked with markedly reduced risk of Type 2 diabetes. The aim of this study was to estimate the prevalence of a similar low-risk group in a sample of middle-aged Irish men and women, and determine whether this cluster is associated with a reduced risk of glucose intolerance (IFG and Type 2 diabetes...

12 Oct 2004



The development of insulin resistance is a critical step in the pathogenesis of type 2 diabetes. The effect of alcohol intake on insulin sensitivity/resistance is not well defined. The aim of this study was to examine the association between alcohol intake and insulin resistance in a sample of middle-aged men and women with data on a wide range of potential confounding factors, including diet.


We performed a cross sectional stu...